Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
ABclonal Technology Phospho-AKT1-T308 Rabbit pAb
Supplier: ABclonal Technology AP0304500UL
This gene encodes a member of the AKT serine-threonine kinase family, which regulates key cellular functions such as cell proliferation, survival, metabolism, and angiogenesis. AKT proteins are activated by phosphorylation through the PI3K pathway and play a central role in signaling involving receptor tyrosine kinases, G-protein coupled receptors, and integrin-linked kinases. Activation of AKT involves phosphorylation of specific residues, including threonine 308 and serine 473. AKT also participates in the mTOR pathway, which is crucial for translation initiation and often dysregulated in cancers. Mutations in this gene are linked to multiple cancers, including breast, colorectal, and ovarian, as well as conditions like Proteus and Cowden syndrome. Alternative splicing of this gene results in multiple transcript variants.
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction