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Medchemexpress LLC AP14145 hydrochloride | 2387505-59-9 | 98.3% | 5 MG
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Supplier:  Medchemexpress LLC HY120355A5MG

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AP14145 hydrochloride is a hydrochloride salt of a small-molecule negative allosteric modulator of KCa2 (SK) channels. It shows in vitro potency near 1.1 μM for KCa2.2 (SK2) and KCa2.3 (SK3) and has demonstrated prolongation of atrial effective refractory period and antiarrhythmic effects in preclinical models. Supplied as a 5 MG vial with reported purity of 98.3%.

  • Negative allosteric modulator of KCa2 (SK) channels
  • In vitro potency around 1.1 μM for SK2 and SK3
  • Demonstrated atrial electrophysiology effects in vivo
  • Hydrochloride salt form for improved handling
  • High reported purity (98.3%)

Catalog No. 50-002-33511


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