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ABclonal Technology APC Mouse anti-Human CD11b mAb
Supplier: ABclonal Technology A27195500T
This gene encodes the integrin alpha M chain Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ( Mac-1 ) or inactivated-C3b (iC3b) receptor 3 ( CR3 ) The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium and also in the phagocytosis of complement coated particles Multiple transcript variants encoding different isoforms have been found for this gene
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