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Medchemexpress LLC Aphidicolin | 38966-21-1 | MFCD00083214 | 1 ML
Supplier: Medchemexpress LLC HYN673310MM/1ML
Aphidicolin is an inhibitor of DNA polymerase α and δ, which prevents mitotic cell division by interfering with DNA polymerase activity. It is an antibiotic produced by the mold Cephalosporium aphidicola. Aphidicolin inhibits cellular deoxyribonucleic acid synthesis and the growth of herpes simplex virus. It also demonstrates anti-orthopoxvirus activity and enhances apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line.
- Inhibits DNA polymerase α and δ
- Prevents mitotic cell division
- Inhibits cellular deoxyribonucleic acid synthesis
- Inhibits the growth of herpes simplex virus
- Shows anti-orthopoxvirus activity
- Enhances apoptosis induced by arabinosyl nucleosides in human promyelocytic leukemia cells
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