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Medchemexpress LLC Aphidicolin | 38966-21-1 | MFCD00083214 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHYN6733

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Aphidicolin is an inhibitor of DNA polymerase α and δ, which functions by interfering with DNA polymerase activity to prevent mitotic cell division. This antibiotic, originating from the mold Cephalosporium aphidicola, is known for its ability to inhibit cellular deoxyribonucleic acid synthesis and the growth of herpes simplex virus. Furthermore, it demonstrates anti-orthopoxvirus activity and enhances apoptosis when induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line.

  • Inhibits DNA polymerase α and δ
  • Prevents mitotic cell division
  • Functions as an antibiotic
  • Inhibits cellular deoxyribonucleic acid synthesis
  • Inhibits growth of herpes simplex virus
  • Exhibits anti-orthopoxvirus activity
  • Potentiates apoptosis induced by arabinosyl nucleosides
  • Targets DNA/RNA synthesis, HSV, and apoptosis pathways
  • Applied in infection and inflammation/immunology research

Catalog No. 50-004-20551


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