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AdipoGen Apicidin

Supplier: AdipoGen AGCN20087M005
Chemical. CAS 183506-66-3. Formula C34H49N5O6. MW 623.8. Isolated from fungus Fusarium sp. Antiprotozoal. Potent inhibitor of histone deacetylase HDAC. Inhibits proliferation. Induces cell cycle arrest at the G1 phase. Induces hyperacetylation of histone H4. Apoptosis inducer. Potent anti-angiogenic compound. Decreases HIF-1alpha protein levels and transcriptional activity in human and mouse tumor cell lines. Autophagy inducer in oral squamous cell carcinoma OSCC cells. Promotes either self-renewal or differentiation of embryonic stem cells.
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