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Cayman Chemical ApIum graveolens ApIIn 10mg

Supplier: Cayman Chemical 3459610 MG

An alkaloid with diverse biological activities inhibits 5-HT reuptake by OCT2 and dopamine reuptake by OCT3 (IC50s 0.137 and 0.354 UM respectively for human recombinant transporters) as well as reduces dopamine 5-HT and norepinephrine reuptake in mouse brain synaptosomes decreases immobility time in the forced swim test in a mouse model of depression induced by chronic unpredictable mild stress at 1.5 and 3 mg/kg reduces acetic acid-induced writhing in mice and increases the mechanical paw withdrawal threshold in a mouse model of bone cancer pain at 10 mg/kg
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