Apexbio Technology LLC Apixaban 503612-47-3 200mg

Supplier:  Apexbio Technology LLC A4341200

Apixaban (CAS 503612-47-3) is a highly selective reversible inhibitor of coagulation Factor Xa with Ki values of 0 08 nM and 0 17 nM for human and rabbit enzymes respectively By targeting Factor Xa a central serine protease in the coagulation cascade apixaban effectively impedes thrombin generation and subsequent clot formation In vitro apixaban prolongs coagulation parameters in human plasma at submicromolar concentrations and demonstrates potent antithrombotic activity across multiple animal models With favorable pharmacokinetics including high oral bioavailability and low clearance in preclinical studies apixaban serves as a valuable tool for investigating coagulation mechanisms and evaluating anticoagulant strategies

Catalog No. 50-000-96389