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Medchemexpress LLC Aplaviroc hydrochloride | 461023-63-2 | 99.9% | 614.17 | 100 MG

Supplier: Medchemexpress LLC HY17450A100MG
Aplaviroc hydrochloride is a potent CCR5 antagonist, effective against wild-type R5 HIV-1 strains with IC50 values of 0.1 to 0.4 nM. It also suppresses the infectivity and replication of HIV-1MDR variants at low concentrations. This compound binds to CCR5 with high affinity and has been shown to suppress R5 HIV-1 viremia in animal models. Aplaviroc hydrochloride has been involved in multiple clinical trials for HIV infection.
- Potent CCR5 antagonist
- Effective against wild-type R5 HIV-1 strains
- Suppresses HIV-1MDR variants
- Binds to CCR5 with high affinity
- Suppresses R5 HIV-1 viremia in animal models
- Investigated in clinical trials for HIV infection
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