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Medchemexpress LLC Aplaviroc hydrochloride | 461023-63-2 | 99.9% | 614.17 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY17450A100MG

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Aplaviroc hydrochloride is a potent CCR5 antagonist, effective against wild-type R5 HIV-1 strains with IC50 values of 0.1 to 0.4 nM. It also suppresses the infectivity and replication of HIV-1MDR variants at low concentrations. This compound binds to CCR5 with high affinity and has been shown to suppress R5 HIV-1 viremia in animal models. Aplaviroc hydrochloride has been involved in multiple clinical trials for HIV infection.

  • Potent CCR5 antagonist
  • Effective against wild-type R5 HIV-1 strains
  • Suppresses HIV-1MDR variants
  • Binds to CCR5 with high affinity
  • Suppresses R5 HIV-1 viremia in animal models
  • Investigated in clinical trials for HIV infection

Catalog No. 50-003-86676


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