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TARGETMOL CHEMICALS INC APRICITABINE 10MG

Supplier: TARGETMOL CHEMICALS INC T1431310MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 uM) the (-) enantiomer of 2′-deoxy-3′-oxy-4′-thiocytidine (dOTC) . Apricitabine inhibits DNA polymerase (alpha) (beta) and (gamma) with Ki values of 300 uM 12 uM and 112.25 uM respectively. Apricitabine has shown good antiretroviral therapeutic efficacy in antiretroviral HIV-infected patients with good tolerability and low selective resistance. purity: 100%
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