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Cayman Chemical ARA 290acetate 1mg
Supplier: Cayman Chemical 349431 MG
An adenosine A2A receptor antagonist (Ki 12 nM) selective for adenosine A2A receptors over adenosine A1- A2B- and A3 receptors (Kis 2500 1000 and 5000 nM respectively) increases the levels of IFN-Y secreted by tumor-associated T cells isolated from patient-derived lung tumors at 1 UM when used in combination with an antibody targeting PD-1 or PD-L1 reduces the number of lung nodules in an MCA-205 murine fibrosarcoma model of lung metastasis at 15 mg/kg per day inhibits haloperidol-induced catalepsy in a rat model of Parkinsons disease motor symptoms at 3 10 or 30 mg/kg
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