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Cayman Chemical ArachIdonIc ACD 1 2 3 4 513

Supplier: Cayman Chemical 17336250 UG

A pan Akt inhibitor (Ki 160 pmol/L for all three isoforms) that interferes with mitotic progression and bipolar spindle formation slows the progression of Akt-dependent tumors in vivo concomitantly increases Akt Thr308 and Ser473 phosphorylation via a rapid feedback reaction
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