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Cayman Chemical ArachIdonIc ACD sulfonatS
SDP

Supplier:  Cayman Chemical 9001886100 UG

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An M4 muscarinic receptor PAM selective for M4 mAChRs over a panel of 59 receptors ion channels transporters and enzymes at 10 UM selectively potentiates ACh-induced activation of the M4 mAChR over M1-M3 and M5 mAChRs in cells expressing the human receptors (EC50s 12.3 4798 >10000 >10000 and >10000 nM respectively) inhibits amphetamine-induced locomotor activity in mice and prepulse inhibition deficits in rats at 3.2 mg/kg

Catalog No. 50-289-5754


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