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Medchemexpress LLC ARC19499 sodium | 1 MG
SDP

Supplier:  Medchemexpress LLC HY153480A1MG

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ARC19499 sodium is an aptamer that functions by inhibiting tissue factor pathway inhibitor (TFPI), which in turn allows for the initiation and propagation of clot formation via the extrinsic pathway. The core aptamer has a strong and specific binding affinity for TFPI.

  • Blocks TFPI inhibition of both factor Xa and the TF/factor VIIa complex.
  • Corrects thrombin generation in plasma from individuals with hemophilia A and B.
  • Restores clotting in whole blood where FVIII has been neutralized.

Catalog No. 50-003-72759


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