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AdipoGen (-)-Arctigenin (10 mg)
SDP

Supplier:  AdipoGen AGCN20530M010

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Chemical. CAS: 7770-78-7. Formula: C21H24O6. MW: 372.4. Semi-Synthetic. Aglycone metabolite of (-)-Arctiin (AG-CN2-0532), isolated from Arctium lappa. Multifunctional natural compound with antioxidant, antibacterial, anti-inflammatory, antidiabetic, neuroprotective, antiproliferative and antiviral activities. Natural agonist of the PP2A that has potent renoprotective effects in type 1 and type 2 diabetic animal models. Inhibits adipogenesis through AMPK induction. Modulator of peroxisome proliferator-activated receptor gamma (PPARgamma). Inhibits LPS-induced iNOS expression via inhibition of IkappaBalpha phosphorylation and p65 nuclear translocation. Inhibits NLRP3 in a SIRT1-dependent manner. HIV-1 integrase/replication inhibitor in vitro. Potently inhibits MKK1 (MEK1). Blocks the activation of Akt induced by glucose starvation in pancreatic cancer PANC-1 cells.

Catalog No. 50-205-3707


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