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Enzo Life Sciences (-)-Arctigenin (25mg). CAS: 7770-78-7
Supplier: Enzo Life Sciences ALX350312M025
Lignan derivative, which shows antitumor, anti-inflammatory, immunomodulatory and neuroprotective activities. Down-regulates anti-apoptotic protein Bcl-XL. Potent inhibitor of HIV type-I integrase and DNA topoisomerase II. Shows phytoestrogenic and cytotoxic properties against Hep62 cells. Antagonist for platelet activating factor and Ca2+. Blocks the activation of Akt (protein kinase B; PKB) induced by glucose starvation. Alternative name: (3R,4R)-4-[(3,4-Dimethoxyphenyl)methyl]dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2-(3H)-furanone. Purity: ≥97% (HPLC). Appearance: Colorless crystals. Solubility: Soluble in DMSO (34mg/ml, heating, sonication); sparingly soluble in water. Long Term Storage: -20°C.
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