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AdipoGen (-)-Arctiin (10 mg)
Supplier: AdipoGen AGCN20532M010
Chemical. CAS: 20362-31-6. Formula: C27H34O11. MW: 534.6. Isolated from Arctium lappa. Metabolizes into (-)-Arctigenin (AG-CN2-0530). Multifunctional natural compound with photoprotective, anti-inflammatory, antidiabetic, antiproliferative and antiviral activities. Decreasing the production of nitric oxide and pro-inflammatory cytokines, such as IL-1beta, IL-6, TNF-alpha and PGE2 through the inhibition of PI3K/AKT/NF-kappaB signaling pathway. Suppresses cyclin D1 protein expression in multiple types of human tumor cells. Inhibitor of HIV-I integrase. Inhibits adipogenesis in 3T3-L1 adipocytes through the inhibition of PPARgamma and C/EBPalpha and the activation of AMPK signaling pathways. Photoprotective agent showing UVB protection in keratinocytes, which is mediated by miRNA responses and the suppression of UVB-induced cell death. Inhibitor of STAT3 phosphorylation at tyrosine 705 residue.
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