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Apexbio Technology LLC Arcyriaflavin A 118458-54-1 1mg
Supplier: Apexbio Technology LLC B70631
Arcyriaflavin A (CAS 118458-54-1) is a small-molecule inhibitor targeting the cyclin-dependent kinase 4 (CDK4)/cyclin D1 complex and CaMKII It is designed to inhibit these kinases thereby modulating cell cycle progression and related signaling pathways Arcyriaflavin A exerts its biological activity primarily through inhibition of CDK4/cyclin D1 and CaMKII In cell-based assays Arcyriaflavin A inhibits the CDK4/cyclin D1 kinase complex with an IC of approximately 59 nM and suppresses human cytomegalovirus (HCMV) replication with an IC of around 0 2 M Based on these pharmacological properties Arcyriaflavin A holds research potential in studies of cell cycle regulation antiviral mechanisms and kinase-inhibitor interactions
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