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Medchemexpress LLC ARD-2585 | 2757422-79-8 | 98.19% | 763.28 | 50 MG
Supplier: Medchemexpress LLC HY13943650MG
ARD-2585 is an exceptionally potent and orally active PROTAC degrader of the androgen receptor, intended for research use only. It achieves DC50 values of 0.04-0.1 nM in the VCaP cell line with AR gene amplification and in the LNCaP cell line carrying an AR mutation. ARD-2585 (100 nM) is effective in reducing the AR protein level by 78% at 3 hours and 60% at 6 hours.
- Purity: 98.19%
- Molecular weight: 763.28
- Formula: C41H43ClN8O5
- Appearance: Solid
- Color: Light yellow to green yellow
- Cellular effect: Achieves DC50 values of 0.04-0.1 nM in VCaP and LNCaP cell lines.
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