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Medchemexpress LLC ARD-61 | 2316837-08-6 | 99.6% | 1095.78 | 25 MG
Supplier: Medchemexpress LLC 25MGHY139659
ARD-61 is a potent PROTAC androgen receptor (AR) degrader. It effectively degrades AR and progesterone receptors (PR) in AR+ cancer cell lines, induces apoptosis, and inhibits tumor growth in xenograft models. It also functions as a click chemistry reagent with an alkyne group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
- Degrades androgen receptor (AR) and progesterone receptors (PR).
- Induces apoptosis in cancer cells.
- Inhibits tumor growth in xenograft models.
- Click chemistry reagent with an alkyne group for CuAAc.
- Induces G2/M cell cycle arrest.
- Inhibits Wnt/β-catenin and MYC pathways.
- Decreases HER2 and HER3 proteins (phosphorylated and un-phosphorylated).
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