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Medchemexpress LLC ARD-69 50mg | 2316837-10-0 | 50 MG

Supplier: Medchemexpress LLC HY11440250MG
ARD-69 is a PROTAC small-molecule degrader that targets the androgen receptor (AR) and is used in preclinical research to investigate AR signaling and castration-resistant prostate cancer. It recruits the VHL E3 ligase to promote ubiquitination and proteasomal degradation of AR, resulting in decreased AR-driven transcription and inhibited proliferation in AR-positive cell lines.
- Used for preclinical studies of AR degradation and prostate cancer models.
- Potent AR degrader with low-nanomolar cellular activity.
- High chemical purity suitable for biological assays.
- Soluble in DMSO at ≥ 200 mg/mL for in vitro formulation.
- Stable under recommended storage when protected from light.
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