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Cayman Chemical ArecaIdIn propargyl esTRh 10mg
Supplier: Cayman Chemical 3456810 MG
A muscarinic M2 agonist; selectively binds to M2 over M1, M3, M4, and M5 mAChRs in CHO cells expressing the human receptors (Kis = 0.0871, 1.23, 0.851, 0.977, and 0.933 µM, respectively); induces contractions in isolated guinea pig atrium (pD2 = 8.67); induces apoptosis and the production of ROS in U87 and U251 cells at 100 µM; decreases mean arterial blood pressure in normotensive cats (ED25 = 1.9 nmol/kg)
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