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CPC Scientific H-Arg-Glu(EDANS)-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(DABCYL)-Arg (trifluoroacetate salt) 0.5MG
Supplier: CPC Scientific AMYD045A
Fluorogenic substrate for pro-memapsin-2 containing the beta-secretase site of the Swedish mutation of APP. The kinetic parameters at pH 4.5 are Km = 5.4 ?M and kcat = 0.24 min-1.ONE-LETTER SEQUENCE: R-E(EDANS)-EVNLDAEF-K(DABCYL)-R MOLECULAR FORMULA: C91H129N25O25S1MOLECULAR WEIGHT:2005.2STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [310427-94-2], RESEARCH AREA: Alzheimer's DiseaseREFERENCES: A.K. Ghosh et al., J. Amer. Chem. Soc., 122, 3522 (2000); J. Ermolieff et al., Biochemistry, 39, 12450 (2000)
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