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Apexbio Technology LLC Argatroban 74863-84-6 10mM (in 1mL DMSO)

Supplier: Apexbio Technology LLC A83635.1

Argatroban is a synthetic small-molecule inhibitor acting as a direct binder to thrombin s active site thereby blocking the thrombin-mediated conversion of fibrinogen into fibrin It competitively inhibits thrombin-induced platelet activation and blood clot formation exhibiting an inhibitory constant (Ki) of approximately 19 nM Due to its specificity and direct mechanism Argatroban is frequently employed in experimental research scenarios to investigate thrombin-dependent coagulation pathways platelet aggregation studies and antithrombotic effects in various in vitro assays and animal thrombosis models
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