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Cayman Chemical Arhalofenate 10mg

Supplier: Cayman Chemical 3457510 MG
A prodrug form of a PPARγ partial agonist; has weak transactivation and strong transrepression activity; reduces fasting plasma glucose levels in ob/ob mouse and ZDF rat models of type 2 diabetes at 125 and 100 mg/kg, respectively; decreases fasting plasma free fatty acid, triglyceride, and cholesterol levels in ZDF rats without increasing body weight at 100 mg/kg; prevents leukocyte and neutrophil infiltration and IL-1β, IL-6, and CXCL1 production in air pouch fluid in a mouse model of gout at 250 mg/kg
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