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Cayman Chemical ArIstolochIc AcId 10mg
Supplier: Cayman Chemical 2152010 MG
A PLA2 inhibitor (IC50 = 40 µM in human neutrophils); inhibits human synovial fluid PLA2-induced edema in a dose-dependent manner in vivo; inhibits hemolytic activity of the PLA2 enzymes TFV PL-X, TFV PL-Ia, and TFV PL-Ib from T. flavoviridis venom (IC50s = 4.6, 4.0, and 3.9 µM, respectively); enhances the edema-inducing activity of TFV PL-Ia and TFV PL-Ib; associated with progressive interstitial fibrosing nephropathy and upper urinary tract urothelial carcinomas
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