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Cayman Chemical ArIstolochIc AcId C 10mg

Supplier: Cayman Chemical 2850510 MG

A partial agonist for a4B2 subunit-containing nAChRs (EC50 0 18 UM) selective for a4B2 over a2B4 a4B4 a3B4 a3B2 and a7 subunit-containing nAChRs (EC50s 14 12 5 30 100 and 100 UM respectively) increases dopamine cell firing in the rat VTA in vitro enhances inhibitory synaptic transmission in dorsal horn neurons via a4B2 subunit-containing nAChRs reduces formalin-induced paw-licking time in mice at 3 and 10 mg/kg reverses scopolamine-induced cognitive deficits in rats in a step-through passive avoidance test at 3 and 6 Umol/kg
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