Medchemexpress LLC Arnicolide D | 34532-68-8 | 10 MG

Supplier:  Medchemexpress LLC HYN684310MG

Arnicolide D is a sesquiterpene lactone isolated from Centipeda minima. It demonstrates cytotoxicity against tumor cells, inducing cell cycle arrest, apoptosis, and oncosis. Arnicolide D exhibits anti-tumor activity.

• Antitumor agent: Is cytotoxic to tumor cells and has anti-tumor activity.
• Induces cell cycle arrest and apoptosis in nasopharyngeal carcinoma cells by activating the caspase signaling pathway and inhibiting the PI3K/AKT/mTOR and STAT3 signaling pathways.
• Induces endoplasmic reticulum stress-mediated and ROS-dependent oncosis in hepatocellular carcinoma cells via ATF4 and CHOP.
• Demonstrates anti-melanoma effects and inhibits the NF-κB pathway in an in vivo B16F10 allograft mouse model.
• High purity of 99.69%.
• Solid, white to off-white appearance.

Catalog No. 50-004-21017