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Medchemexpress LLC Arnicolide D | 34532-68-8 | 10 MG
SDP

Catalog No. 5000421017
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Arnicolide D is a sesquiterpene lactone isolated from Centipeda minima. It demonstrates cytotoxicity against tumor cells, inducing cell cycle arrest, apoptosis, and oncosis. Arnicolide D exhibits anti-tumor activity.

  • Antitumor agent: Is cytotoxic to tumor cells and has anti-tumor activity.
  • Induces cell cycle arrest and apoptosis in nasopharyngeal carcinoma cells by activating the caspase signaling pathway and inhibiting the PI3K/AKT/mTOR and STAT3 signaling pathways.
  • Induces endoplasmic reticulum stress-mediated and ROS-dependent oncosis in hepatocellular carcinoma cells via ATF4 and CHOP.
  • Demonstrates anti-melanoma effects and inhibits the NF-κB pathway in an in vivo B16F10 allograft mouse model.
  • High purity of 99.69%.
  • Solid, white to off-white appearance.

Catalog No. 50-004-21017 Supplier Medchemexpress LLC Supplier No. HYN684310MG
May include imposed supplier surcharges.
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Arnicolide D is a sesquiterpene lactone isolated from Centipeda minima. It demonstrates cytotoxicity against tumor cells, inducing cell cycle arrest, apoptosis, and oncosis. Arnicolide D exhibits anti-tumor activity.

  • Antitumor agent: Is cytotoxic to tumor cells and has anti-tumor activity.
  • Induces cell cycle arrest and apoptosis in nasopharyngeal carcinoma cells by activating the caspase signaling pathway and inhibiting the PI3K/AKT/mTOR and STAT3 signaling pathways.
  • Induces endoplasmic reticulum stress-mediated and ROS-dependent oncosis in hepatocellular carcinoma cells via ATF4 and CHOP.
  • Demonstrates anti-melanoma effects and inhibits the NF-κB pathway in an in vivo B16F10 allograft mouse model.
  • High purity of 99.69%.
  • Solid, white to off-white appearance.

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