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Medchemexpress LLC ARS-1323 | 1698024-73-5 | 430.84 | 10 MG
Supplier: Medchemexpress LLC HYU0041610MG
ARS-1323 is a KRAS G12C inhibitor that specifically binds to the cysteine residue on the mutant K-Ras protein, locking it in the GDP-bound conformation. This action blocks K-Ras activation and downstream signaling pathways. It can be used to investigate signal transduction mechanisms and growth characteristics of tumor cells driven by K-Ras G12C.
- Targets Ras
- Inhibits GPCR/G Protein and MAPK/ERK pathway
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 2 years, -20°C for 1 year
- Solubility in DMSO: 100 mg/mL (232.10 mM)
- In vivo solubility options available
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