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Medchemexpress LLC Ars-1323-alkyne | 2436544-27-1 | MFCD32067946 | 99.6% | 569.00 g/mol | C28H27ClF2N6O3 | 5 MG
Supplier: Medchemexpress LLC HY1285225MG
ARS-1323-alkyne is a covalent inhibitor probe that selectively targets the Switch-II pocket (S-IIP) of KRAS G12C. It is used to visualize covalent modification and to quantify inhibitor binding and target occupancy in biochemical and cellular studies; for research use only.
- Covalent binding to the KRAS G12C Switch-II pocket.
- Alkyne handle enables click-chemistry labeling and detection.
- High purity (99.6%) suitable for biochemical and cellular assays.
- Soluble in DMSO (250 mg/mL) and formulatable for in vivo dosing protocols.
- Recommended storage: solid at 4°C under nitrogen; store solutions frozen for stability.
- Molecular formula C28H27ClF2N6O3; molecular weight 569.00 g/mol.
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