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Medchemexpress LLC Ars-1630 | 1698055-86-5 | 430.84 | 10 MG
Supplier: Medchemexpress LLC HYU0041710MG
This compound is a novel inhibitor of mutant K-ras G12C, derived from patent WO 2015054572 A1. It is intended for research use only and not for patient administration.
- Inhibitor of mutant K-ras G12C.
- Utilizes allele-specific covalent targeting of Cys-12.
- Targets an inducible allosteric switch II pocket.
- Requires active cycling between active-GTP and inactive-GDP conformations for targeting.
- Demonstrates feasibility for inhibiting mutant KRAS in laboratory settings.
- High purity (98.10%).
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