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Cayman Chemical ArtemIsInIn 100mg

Supplier: Cayman Chemical 11816100 MG
An antimalarial agent with anticancer activity; an iron(II) oxide-reactive endoperoxide that generates ROS; reduces the growth of various P. falciparum strains in vitro (IC50s = 3.98-20.36 nM); reduces parasitemia in mice infected with P. falciparum (CD50 = 140 mg/kg); reduces P. berghei infection in mice (ED50 = 5.6 mg/kg per day); inhibits growth of SK-N-AS, BE(2)-C, SK-N-DZ, and SHEP1 neuroblastoma cells from 100-400 μM; suppresses BE(2)-C cell colony formation in a soft agar assay and reduces tumor growth in a BE(2)-C mouse xenograft model
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