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Medchemexpress LLC Articaine hydrochloride | 23964-57-0 | 99.4% | 1 ML
Supplier: Medchemexpress LLC HYB051610MM/1ML
Articaine hydrochloride is a selective inhibitor of voltage-gated sodium channels, demonstrating local anesthetic activity by blocking nerve impulse conduction. It also exhibits anti-inflammatory functions by inhibiting NF-κB activation and NLRP3 inflammasome pathways. It is used in the study of dental local anesthesia and inflammatory-related diseases.
- Inhibits voltage-gated sodium channels
- Exhibits local anesthetic activity
- Inhibits NF-κB activation and NLRP3 inflammasome pathways
- Reduces inflammatory factors like TNF-α, IL-6, and IL-1β
- Ameliorates LPS-induced acute kidney injury in animal models
- Can enhance anesthetic effect in zebrafish model
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