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Medchemexpress LLC Articaine hydrochloride | 23964-57-0 | 99.4% | 500 MG
Supplier: Medchemexpress LLC HYB0516500MG
Articaine hydrochloride is a selective inhibitor of voltage-gated sodium channels, exerting local anesthetic activity by inhibiting Na+ influx to block nerve impulse conduction. It also inhibits NF-κB activation and NLRP3 inflammasome pathways, demonstrating anti-inflammatory function. This compound is used in the study of dental local anesthesia and inflammatory-related diseases, such as acute kidney injury.
- Selective inhibitor of voltage-gated sodium channels (rNav1.4, hNav1.7, and rNav1.8)
- Inhibits Na+ influx to block nerve impulse conduction
- Exhibits local anesthetic activity
- Inhibits NF-κB activation and NLRP3 inflammasome pathways
- Demonstrates anti-inflammatory function
- Applicable in dental local anesthesia research
- Applicable in inflammatory-related diseases research, such as acute kidney injury
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