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Bachem BKT140 Acetate

Supplier: Bachem 4073017.1000

BKT140 Acetate, 4-Fluorobenzoyl-Arg-Arg-2-Nal-Cys-Tyr-Cit-Lys-D-Lys-Pro-Tyr-Arg-Cit-Cys-Arg-NH2, 664334-36-5, C97H144FN33O19S2, Mr 2159.55, 1mg. 4F-benzoyl-TN14003, BL-8040. As described by Peled and coworkers, BKT140 (4F-benzoyl-TN14003) is a biostable, high-affinity chemokine receptor CXCR4 antagonist, which binds CXCR4 with a greater affinity than plerixafor. When combined with G-CSF (granulocyte colony-stimulating factor), BKT140 is a safe and efficient stem cell mobilizer that enabled the collection of a high number of CD34+ cells in 1 and 2 aphaeresis procedures, resulting in successful engraftment.
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