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Medchemexpress LLC AS057278 | 402-61-9 | 99.76% | 126.11 | 200 MG
Supplier: Medchemexpress LLC HY33009200MG
AS057278 is a potent, selective, orally active, and blood-brain barrier (BBB) penetrant non-peptidic D-amino acid oxidase (DAAO) inhibitor with an IC50 value of 0.91 μM and EC50 of 2.2-3.95 μM. It can normalize phencyclidine (PCP)-induced prepulse inhibition in mice and can be used for researching schizophrenia.
- Inhibits D-amino acid oxidase (DAAO)
- Potent, selective, orally active, and BBB penetrant
- Normalizes phencyclidine (PCP)-induced prepulse inhibition in mice
- Exhibits good pharmacokinetic effects in male Sprague-Dawley rats
- Appearance: solid, light yellow to light brown
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
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