Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000343465

Medchemexpress LLC AS601245 | 345987-15-7 | 98.2% | 372.45 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY11010100MG

Encompass_Preferred

AS601245 is an orally active, selective, ATP competitive JNK (c-Jun NH2-terminal protein kinase) inhibitor. It targets hJNK1, hJNK2, and hJNK3 isoforms and demonstrates significant selectivity over various other protein kinases. This compound exhibits neuroprotective properties and can be used in different in vitro and in vivo studies.

  • Orally active, selective, ATP competitive JNK inhibitor
  • Exhibits neuroprotective properties
  • Shows selectivity over c-src, CDK2, c-Raf, and other Ser/Thr- and Tyr-protein kinases
  • Synergistic effects with Clofibrate in CaCo-2 colon cancer cells
  • Provides significant protection against delayed loss of hippocampal CA1 neurons in gerbil models of transient global ischemia
  • Potent inhibitor of LPS-induced TNF-α release in mice

Catalog No. 50-003-43465


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.