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Medchemexpress LLC Asenapine hydrochloride | 1412458-61-7 | 99.95% | 322.23 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY165675MG

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Asenapine (Org 5222) hydrochloride is an atypical antipsychotic. It acts as an antagonist of serotonin receptors (pKi: 8.4-10.5), adrenoceptors (pKi: 8.9-9.5), dopamine receptors (pKi: 8.9-9.4), and histamine receptors (pKi: 8.2-9.0). This product can be utilized in research pertaining to schizophrenia and bipolar disorder.

  • Antagonist of various serotonin receptors (5-HT1A, 5-HT1B, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT6, 5-HT7).
  • Antagonist of adrenergic receptors (α2A, α2B, α2C).
  • Antagonist of dopamine receptors (D2, D3, D4).
  • Antagonist of histamine receptors (H1).
  • Investigated for its use in schizophrenia and bipolar disorder research.
  • Shown to reduce anxiety-related behaviors in rat conditioned fear stress models.
  • Exhibits anxiolytic-like effects in mice.

Catalog No. 50-003-94489


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