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Medchemexpress LLC Asenapine hydrochloride (Org 5222 hydrochloride) | 1412458-61-7 | 99.95% | 322.23 | 50 MG
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Supplier:  Medchemexpress LLC HY1656750MG

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Asenapine hydrochloride (Org 5222) is an atypical antipsychotic primarily investigated for its role in schizophrenia and bipolar disorder research. It acts as a potent antagonist across a diverse range of receptors, including serotonin, adrenoceptors, dopamine, and histamine.

  • Exhibits higher affinity for 5-HT2C, 5-HT2A, 5-HT2B, 5-HT7, 5-HT6, α2B, and D3 receptors relative to its D2 receptor affinity.
  • Potent antagonist (pKB) at 5-HT1A (7.4), 5-HT1B (8.1), 5-HT2A (9.0), 5-HT2B (9.3), 5-HT2C (9.0), 5-HT6 (8.0), 5-HT7 (8.5), D2 (9.1), D3 (9.1), α2A (7.3), α2B (8.3), α2C (6.8), and H1 (8.4) receptors.

Catalog No. 50-003-94243


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