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Medchemexpress LLC Asenapine maleate | 85650-56-2 | 99.95% | 401.84 | 10 MM 1 ML
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Supplier:  Medchemexpress LLC HY1110010MM/1ML

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Asenapine maleate (Org 5222 maleate) is a brain-penetrant atypical antipsychotic. It acts as an antagonist for serotonin receptors (pKi: 8.4-10.5), adrenoceptors (pKi: 8.9-9.5), dopamine receptors (pKi: 8.9-9.4), and histamine receptors (pKi: 8.2-9.0). This compound is utilized in research for conditions such as schizophrenia and bipolar disorder.

  • Antagonist of serotonin, adrenoceptors, dopamine, and histamine receptors.
  • Brain-penetrant atypical antipsychotic.
  • Used in schizophrenia and bipolar disorder research.
  • Higher affinity for 5-HT2C, 5-HT2A, 5-HT2B, 5-HT7, 5-HT6, α2B and D3 receptors relative to D2.
  • May offer superior therapeutic effects on anxiety.
  • Demonstrates anxiolytic-like effects in animal models.

Catalog No. 50-003-43655


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