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Cayman Chemical -Asenapn 10mg
Supplier: Cayman Chemical 900049610 MG
An atypical antipsychotic; binds to dopamine D1-4, α-adrenergic, and histamine receptors (Kis = 0.42-1.45, 0.32-1.26, and 1-6.17 nM, respectively), as well as various 5-HT receptors (Kis = 0.03-3.98 nM); inhibits DOI, apomorphine, or clonidine-induced neuron firing in rat brain (ED50s = 75, 40, and 85 μg/kg, respectively); increases mPFC, NAc, and lateral striatum extracellular dopamine and suppresses the conditioned avoidance response in rats from 0.05-0.2 mg/kg, s.c.; prevents acute and chronic phencyclidine-induced deficits in cued reversal learning in rats at 0.075 mg/kg
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