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Medchemexpress LLC Asp-AMS, an analogue of aspartyl-adenylate | 828288-98-8 | 98.1% | 461.41 | 10 MG
SDP

Catalog No. 5000437762
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Asp-AMS is an analogue of aspartyl-adenylate. It functions as an aspartyl-tRNA synthetase inhibitor and a potent competitive inhibitor of the mitochondrial enzyme. It is intended for research use only.

  • Analogue of aspartyl-adenylate.
  • Aspartyl-tRNA synthetase inhibitor.
  • Strong competitive inhibitor of the mitochondrial enzyme.
  • 500-fold stronger competitive inhibitor of the mitochondrial enzyme than aspartol-AMP (10 nM).
  • 35-fold lower competitor of human and bovine cyt-AspRSs (300 nM).
  • Strong inhibitor with Ki in the nanomolar (nM) range.
  • Highest inhibitory effect for the mitochondrial enzyme.
  • Most active inhibitor with Ki values in the nanomolar range.
  • Stronger effect on bacterial AspRSs (E. coli and P. aeruginosa) than on human cytosolic AspRS.

Catalog No. 50-004-37762 Supplier Medchemexpress LLC Supplier No. HY11286010MG
May include imposed supplier surcharges.
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Asp-AMS is an analogue of aspartyl-adenylate. It functions as an aspartyl-tRNA synthetase inhibitor and a potent competitive inhibitor of the mitochondrial enzyme. It is intended for research use only.

  • Analogue of aspartyl-adenylate.
  • Aspartyl-tRNA synthetase inhibitor.
  • Strong competitive inhibitor of the mitochondrial enzyme.
  • 500-fold stronger competitive inhibitor of the mitochondrial enzyme than aspartol-AMP (10 nM).
  • 35-fold lower competitor of human and bovine cyt-AspRSs (300 nM).
  • Strong inhibitor with Ki in the nanomolar (nM) range.
  • Highest inhibitory effect for the mitochondrial enzyme.
  • Most active inhibitor with Ki values in the nanomolar range.
  • Stronger effect on bacterial AspRSs (E. coli and P. aeruginosa) than on human cytosolic AspRS.

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