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Cayman Chemical AstragalosIde I 10mg

Supplier: Cayman Chemical 2243110 MG

An anti-migraine agent binds to connexin43 hemichannels and inhibits ATP release in vitro during injury and reperfusion in a dose-dependent manner blocks trigeminal ganglion neuronal-satellite glial cell signaling and cortical spreading depression in vivo (10 mg/kg) increases the seizure threshold in MEST mice and rats (143 and 1192 respectively) blocks neurogenic plasma extravasation in a rat trigeminal nerve migraine model
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