Medchemexpress LLC Astragaloside II | 84676-89-1 | 827.01 | 100 MG

Supplier:  Medchemexpress LLC HYN0433100MG

Astragaloside II is an orally active Cycloartane-type triterpene glycoside extracted from *Astragalus membranaceus*. It is used in the research of diseases such as liver cancer, osteoporosis, immunosuppressive diseases, and ulcerative colitis. It functions by inhibiting autophagy, decreasing pro-inflammatory cytokines (IL-6, IL-1β), HIF-α, p-p65, and p-IκB, and increasing superoxide dismutase (SOD). It also regulates immunity and reduces inflammatory responses.

• Promotes cell viability of rat primary osteoblasts.
• Enhances proliferation of primary splenocytes.
• Sensitizes cells to 5-fluorouracil-induced cell death.
• Inhibits levels of HIF-α, p-p65, and p-IκB, demonstrating an anti-inflammatory effect.
• Alleviates symptoms of DSS-induced ulcerative colitis in mice.
• Reduces DAI score and prevents body weight loss in vivo.
• Increases colon length and superoxide dismutase in colon tissues.

Catalog No. 50-003-89703