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Medchemexpress LLC Astragaloside II | 84676-89-1 | 827.01 | 100 MG
SDP

Catalog No. 5000389703
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Astragaloside II is an orally active Cycloartane-type triterpene glycoside extracted from *Astragalus membranaceus*. It is used in the research of diseases such as liver cancer, osteoporosis, immunosuppressive diseases, and ulcerative colitis. It functions by inhibiting autophagy, decreasing pro-inflammatory cytokines (IL-6, IL-1β), HIF-α, p-p65, and p-IκB, and increasing superoxide dismutase (SOD). It also regulates immunity and reduces inflammatory responses.

  • Promotes cell viability of rat primary osteoblasts.
  • Enhances proliferation of primary splenocytes.
  • Sensitizes cells to 5-fluorouracil-induced cell death.
  • Inhibits levels of HIF-α, p-p65, and p-IκB, demonstrating an anti-inflammatory effect.
  • Alleviates symptoms of DSS-induced ulcerative colitis in mice.
  • Reduces DAI score and prevents body weight loss in vivo.
  • Increases colon length and superoxide dismutase in colon tissues.

Catalog No. 50-003-89703 Supplier Medchemexpress LLC Supplier No. HYN0433100MG
May include imposed supplier surcharges.
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Astragaloside II is an orally active Cycloartane-type triterpene glycoside extracted from *Astragalus membranaceus*. It is used in the research of diseases such as liver cancer, osteoporosis, immunosuppressive diseases, and ulcerative colitis. It functions by inhibiting autophagy, decreasing pro-inflammatory cytokines (IL-6, IL-1β), HIF-α, p-p65, and p-IκB, and increasing superoxide dismutase (SOD). It also regulates immunity and reduces inflammatory responses.

  • Promotes cell viability of rat primary osteoblasts.
  • Enhances proliferation of primary splenocytes.
  • Sensitizes cells to 5-fluorouracil-induced cell death.
  • Inhibits levels of HIF-α, p-p65, and p-IκB, demonstrating an anti-inflammatory effect.
  • Alleviates symptoms of DSS-induced ulcerative colitis in mice.
  • Reduces DAI score and prevents body weight loss in vivo.
  • Increases colon length and superoxide dismutase in colon tissues.

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