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Cayman Chemical AstragalosIde III 10mg
Supplier: Cayman Chemical 2243210 MG
A fluoroquinolone antibiotic active against clinical isolates of S aureus coagulase-negative staphylococci P acnes and P granulosum (MIC50s 0 03 0 06 0 25 and 0 125 mg/L respectively) inhibits the activities of DNA gyrase and topoisomerase IV (IC50s 8 83 and 3 22 mg/L respectively for the S aureus enzymes) inhibits P acnes-induced increases in the production of IFN-Y IL-1B and IL-12p70 in human PBMCs as well as reduces P acnes-induced increases in the production of IL-8 and IL-6 in isolated human keratinocytes reduces the number of skin lesion CFUs in a mouse model of burn wounds infected with S aureus or P acnes when applied topically as a cream at 1
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