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Cayman Chemical AstragalosIde IV 1mg
SDP

Supplier:  Cayman Chemical 120691 MG

Encompass_Preferred

The A1 A2A A2B and A3 adenosne receptors (ARs) are ubqutous G proten-coupled receptors The four AR subtypes have been mplcated n several areas of therapeutc nterest such as stroke and other schemc condtons as well as nflammaton neurodegeneratve dseases dabetes and sleep regulaton 13281 A3 AR antagonsts are of nterest as therapeutc agents n glaucoma agents and nflammaton CAY10498 s a potent and selectve A3 AR antagonst exhbtng a K of 37 nM wth 60 and 200-fold selectvty over A1 and A2A adenosne receptors respectvely 13281 CAY10498 s also a structural analog of reversne a dedfferentaton agent of embryonc progentor cells 12913 However no dedfferentaton effects or any connecton between A3 AR antagonsm and dedfferentaton have been demonstrated

Catalog No. 50-295-5477


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