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TARGETMOL CHEMICALS INC ASTRAGALOSIDE IV 50MG
SDP

Catalog No. 502577025
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Also available in 5 mg 10 mg 25 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Astragaloside IV (AS-IV) an active component isolated from Astragalus membranaceus suppresses the activation of ERK1/2 and JNK and downregulates matrix metalloproteases (MMP)-2 (MMP)-9 in MDA-MB-231 breast cancer cells. Astragaloside IV is a bioactive saponin first isolated from the dried plant roots of the genus Astragalus which is used in traditional Chinese medicine.1 It dose-dependently inhibits human adenovirus type 3 (HAdV-3) in A549 cells (IC50 = 23 uM; LC50 = 865 uM).It inhibits replication of HAdV-3 and decreases HAdV-3-induced apoptosis. It has diverse protective effects for the cardiovascular immune digestive and nervous systems. In particular it reduces myocardial infarct size in dogs when administered prior to coronary ligation and reduces reperfusion arrhythmias in isolated rat hearts. purity: 99%

Catalog No. 50-257-7025 Supplier TARGETMOL CHEMICALS INC Supplier No. T297350MG
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Also available in 5 mg 10 mg 25 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Astragaloside IV (AS-IV) an active component isolated from Astragalus membranaceus suppresses the activation of ERK1/2 and JNK and downregulates matrix metalloproteases (MMP)-2 (MMP)-9 in MDA-MB-231 breast cancer cells. Astragaloside IV is a bioactive saponin first isolated from the dried plant roots of the genus Astragalus which is used in traditional Chinese medicine.1 It dose-dependently inhibits human adenovirus type 3 (HAdV-3) in A549 cells (IC50 = 23 uM; LC50 = 865 uM).It inhibits replication of HAdV-3 and decreases HAdV-3-induced apoptosis. It has diverse protective effects for the cardiovascular immune digestive and nervous systems. In particular it reduces myocardial infarct size in dogs when administered prior to coronary ligation and reduces reperfusion arrhythmias in isolated rat hearts. purity: 99%

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