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Medchemexpress LLC Astressin 2B TFA | 98.5% | 4041.69 | 1 MG
SDP

Catalog No. 5000424775
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Astressin 2B TFA is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist. It blocks protective effects mediated by CRFR2, exacerbating indomethacin-induced hemorrhagic intestinal injury in rats. This compound reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion, and upregulation of inflammatory mediators. It is an important tool molecule for investigating intestinal protective mechanisms of CRFR2.

  • Highly selective CRFR2 antagonist
  • Blocks anxiogenic effect of Urocortin 2
  • Attenuates stress-induced anxiety-related behaviors
  • Exacerbates intestinal epithelial damage in specific models
  • Important tool for investigating intestinal protective mechanisms of CRFR2

Catalog No. 50-004-24775 Supplier Medchemexpress LLC Supplier No. HYP1108A1MG
May include imposed supplier surcharges.
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Astressin 2B TFA is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist. It blocks protective effects mediated by CRFR2, exacerbating indomethacin-induced hemorrhagic intestinal injury in rats. This compound reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion, and upregulation of inflammatory mediators. It is an important tool molecule for investigating intestinal protective mechanisms of CRFR2.

  • Highly selective CRFR2 antagonist
  • Blocks anxiogenic effect of Urocortin 2
  • Attenuates stress-induced anxiety-related behaviors
  • Exacerbates intestinal epithelial damage in specific models
  • Important tool for investigating intestinal protective mechanisms of CRFR2

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