Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000359853

Medchemexpress LLC AT-533 | 908112-37-8 | 98.4% | 410.51 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY14887710MM/1ML

Encompass_Preferred

AT-533 is a potent inhibitor of Hsp90 and HSV, suppressing tumor growth and angiogenesis by blocking the HIF-1α/VEGF/VEGFR-2 signaling pathway. It also inhibits the activation of downstream pathways like Akt/mTOR/p70S6K, Erk1/2, and FAK, and hinders tube formation, cell migration, and invasion in human umbilical vein endothelial cells (HUVECs).

  • Potent Hsp90 and HSV inhibitor
  • Suppresses tumor growth and angiogenesis
  • Blocks HIF-1α/VEGF/VEGFR-2 signaling pathway
  • Inhibits Akt/mTOR/p70S6K, Erk1/2, and FAK pathways
  • Inhibits tube formation, cell migration, and invasion in HUVECs
  • Decreases inflammatory cytokine production in HSV-1 induced cells
  • Shows anti-angiogenic ability

Catalog No. 50-003-59853


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.