Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000359521

Medchemexpress LLC AT-533 | 908112-37-8 | 98.4% | 410.51 | 50 MG
SDP

Catalog No. 5000359521
Encompass_Preferred

AT-533 is a potent inhibitor of Heat Shock Protein 90 (Hsp90) and Herpes Simplex Virus (HSV). It demonstrates anti-tumor and anti-angiogenic properties by targeting the HIF-1α/VEGF/VEGFR-2 signaling pathway, and suppresses downstream pathways including Akt/mTOR/p70S6K, Erk1/2, and FAK.

  • Potent Hsp90 and HSV inhibitor.
  • Suppresses tumor growth and angiogenesis.
  • Inhibits key signaling pathways: Akt/mTOR/p70S6K, Erk1/2, and FAK.
  • Reduces tube formation, cell migration, and invasion in HUVECs.
  • Demonstrates anti-angiogenic activity in CAM models.
  • Decreases inflammatory markers TNF-α, IL-1β, and IL-6.
  • Shows no adverse reactions in subacute toxicology studies.

Catalog No. 50-003-59521 Supplier Medchemexpress LLC Supplier No. HY14887750MG
May include imposed supplier surcharges.
Add to Cart
Add to Cart

AT-533 is a potent inhibitor of Heat Shock Protein 90 (Hsp90) and Herpes Simplex Virus (HSV). It demonstrates anti-tumor and anti-angiogenic properties by targeting the HIF-1α/VEGF/VEGFR-2 signaling pathway, and suppresses downstream pathways including Akt/mTOR/p70S6K, Erk1/2, and FAK.

  • Potent Hsp90 and HSV inhibitor.
  • Suppresses tumor growth and angiogenesis.
  • Inhibits key signaling pathways: Akt/mTOR/p70S6K, Erk1/2, and FAK.
  • Reduces tube formation, cell migration, and invasion in HUVECs.
  • Demonstrates anti-angiogenic activity in CAM models.
  • Decreases inflammatory markers TNF-α, IL-1β, and IL-6.
  • Shows no adverse reactions in subacute toxicology studies.

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.